王红云,女,硕士生导师,讲师。上海市晨光学者,上海市青年科技英才“扬帆计划”获得者。毕业于中国科学院大学,博士期间曾到美国内布拉斯加医学中心访学。目前主持国家自然科学基金青年基金,上海市科委及教委基金,参与国家自然基金重点国际合作项目等。担任《Journal of Cardiovascular Translation Research》等杂志审稿人,《Frontiers in Cardiovascular Medicine》杂志编委。曾获上海市教委新进青年教师岗前培训教学技能大赛特等奖,“龚兰生青年学者奖”二等奖。研究方向包含:

1.大气细颗粒物PM2.5引发心功能紊乱的分子机制;

2.运动保护心血管健康的分子机制(piRNA);

3.外泌体在心血管疾病中的治疗与应用。

代表性论著

1.Wang H, Xie Y, Guan L, Elkin K and Xiao J. Targets identified from exercised heart: killing multiple birds with one stone.NPJ Regen Med. 2021;6:23.

2.Wang H, Xie Y, Salvador AM, Zhang Z, Chen K, Li G and Xiao J*. Exosomes: Multifaceted Messengers in Atherosclerosis.Curr Atheroscler Rep. 22, 57 (2020).

3.Wang H#, Shen X#, Liu J, Wu C, Gao J, Zhang Z, Zhang F, Ding W*and Lu Z*. The effect of exposure time and concentration of airborne PM2.5 on lung injury in mice: A transcriptome analysis.Redox Biology. 2019;26:101264.

4.Wang H, Shen X, Tian G, Shi X, Huang W, Wu Y, Sun L, Peng C, Liu S, Huang Y, Chen X, Zhang F, Chen Y, Ding W*and Lu Z*. AMPKalpha2 deficiency exacerbates long-term PM2.5 exposure-induced lung injury and cardiac dysfunction.Free Radical Biology Medicine. 2018; 202-214.

5. Shi L#, Zhao C#,Wang H#, Lei T, Liu S, Cao J and Lu Z*. Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice.Antioxidant Redox Signaling. 2017; 1347-1360.

6.Wang H, Guo Y, Liu L, Guan L, Wang T, Zhang L, Wang Y, Cao J, Ding W, Zhang F*and Lu Z*. DDAH1 plays dual roles in PM2.5 induced cell death in A549 cells.Biochim Biophys Acta. 2016;2793-2801.

7.Zhou QL, Bai YZ, Gao J, Duan Y, Lyu YC, Guan LF, Elkin K, Xie YL, Jiao Z* andWang H Y*. Human Serum-derived Extracellular Vesicles Protect A549 from PM 2.5-induced Cell Apoptosis. Biomed Environ Sci. 2021;34:40-49.

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