赵婧，女，教授，博士生导师。主要研究方向为针对乳腺癌相关标志物的生化分析与生物传感新方法研究，先后主持国家自然科学基金青年项目一项和面上项目两项以及上海市教委创新项目一项，参与获得了2014年国家教育部高等学校科学研究优秀成果奖（科学技术）自然科学奖二等奖，并于2019年获得上海市“浦江人才”计划资助。在Biosens. Bioelectron.、ACS Appl. Mater. Inter.、Angew. Chem. Int. Edit.、Adv.Funct.Mater.、Theranostics、Anal. Chem.、Chem. Commu.等专业内较高水平SCI期刊上发表论文50余篇，总引用次数超过1100次，单篇最高引用超过200次。

电话 021-66138133

邮箱 jingzhao@t.shu.edu.cn

教育与工作经历

2002-2006年，南京大学生物技术专业，获理学学士学位；

2006-2011年，南京大学生物化学与分子生物学专业，获理学博士学位。

2011年9月进入公司工作，任讲师

2013年6月晋升为副研究员

2017.06-2018.06期间在美国加州大学圣地亚哥分校任访问学者。

2019年3月晋升为教授

主要研究领域

生化分析与生物传感新方法研究

代表性研究成果

基于多肽自组装以及核酸有序组装反应设计了一系列高效的电化学信号放大方案，并依此实现了以乳腺癌干细胞为代表的乳腺癌细胞表面标志物准确且高灵敏的检测目标。

近五年代表性论文

1.   Ya Cao, Lingling Li, Bing Han, Ying Wang, Yuhao Dai, Jing Zhao*, A catalytic molecule machine-driven biosensing method for amplified electrochemical detection of exosomes. Biosensors and Bioelectronics, 2019, 141, 111397.

2.   Ya Cao, Yuhao Dai, Hong Chen, Yingying Tang, Xu Chen, Ying Wang, Jing Zhao*, Xiaoli Zhu*, Integration of fluorescence imaging and electrochemical biosensing for both qualitative location and quantitative detection of cancer cells. Biosensors and Bioelectronics, 2019, 130, 132-138.

3.   Lingling Li, Bing Han, Ying Wang, Jing Zhao*, Ya Cao*, Simple and universal signal labeling of cell surface for amplified detection of cancer cells via mild reduction. Biosensors and Bioelectronics, 2019, 145, 111714.

4.   Yingying Tang, Yuhao Dai, Xiang Huang, Lingling Li, Bing Han, Ya Cao*, Jing Zhao*, Self-assembling peptide-based multifunctional nanofibers for elec-trochemical identification of breast cancer stem-like cells. Analytical Chemistry, 2019, 91, 7531-7537.

5.   Songsong Tang#, Fangyu Zhang#, Jing Zhao#, Wael Talaat, Fernando Soto, Emil Karshalev, Chuanrui Chen, Zhihan Hu, Xiaolong Lu, Jinxing Li, Zhihua Lin, Haifeng Dong, Xueji Zhang, Amir Nourhani, Joseph Wang*, Structure-dependent optical modulation of propulsion and collective behavior of acoustic/light-driven hybrid microbowls. Advanced Functional Materials, 2019, 29, 1809003.

6.   Malthe Hansen-Bruhn#, Berta Esteban-Fernández de Ávila#, Mara Beltrán-Gastélum#, Jing Zhao#, Doris E. Ramírez-Herrera, Pavimol Angsantikul, Kurt Vesterager Gothelf, Liangfang Zhang*, Joseph Wang*. Active intracellular delivery of a Cas9/sgRNA complex using ultrasound-propelled nanomotors. Angewandte Chemie-International Edition, 2018, 57, 2657-2661.

7.   Jing Zhao, Lili Yang, Yuhao Dai, Yingying Tang, Xiuqing Gong, Dongshu Du*, Ya Cao*, Peptide-templated multifunctional nanoprobe for feasible electrochemical assay of intracellular kinase. Biosensors and Bioelectronics, 2018, 119, 42-47.

8.   Xiaoxia Chen#, Jing Zhao#, Tianshu Chen, Tao Gao, Xiaoli Zhu*, Genxi Li*. Nondestructive analysis of tumor-associated membrane protein integrating imaging and amplified detection in situ based on dual-labeled DNAzyme, Theranostics, 2018, 8, 1075-1083.

9.   Chang Feng, Zihan Wang, Tianshu Chen, Xiaoxia Chen, Dongsheng Mao, Jing Zhao*, Genxi Li*, A dual-enzyme-assisted three-dimensional DNA walking machine using T4 polynucleotide kinase as activators and application in polynucleotide kinase assays. Analytical Chemistry, 2018, 90, 2810-2815.

10.  Jing Zhao, Lili Yang, Yingying Tang, Yucai Yang, Yongmei Yin*, Supramolecular chemistry-assisted electrochemical method for the assay of endogenous peptidylarginine deiminases activities. ACS Applied Materials & Interfaces, 2017, 9, 152-158.

11.  Yun Lv, Mengjia Lu, Yucai Yang, Yongmei Yin*, Jing Zhao*, Electrochemical detection of intracellular glutathione based on ligand exchange assisted release of DNA-templated silver nanoparticles. Sensors and Actuators B: Chemical, 2017, 244, 151-156.

12.  Yun Lv, Lili Yang, Xiaoxia Mao, Mengjia Lu, Jing Zhao*, Yongmei Yin*, Electrochemical detection of glutathione based on Hg2+-mediated strand displacement reaction strategy. Biosensors and Bioelectronics, 2016, 85, 664-668.

近五年获发明专利授权

1.   李根喜、赵婧、吕赟、鲁蒙佳，谷胱甘肽检测用生物传感器、其制备方法及其检测方法， 2018.10.23，中国，ZL201610295960.4。

2.   李根喜、赵婧、胡随随、陈稀娴、王乔，检测小分子配体靶蛋白用RCA产物及其检测方法，2017.5.31，中国， ZL201410460134.1。

3.   李根喜、赵婧、吴吉光、仲卫冬、辛美玲，检测凝血酶用生物电化学传感器其制备方法及应用，2016.5.25，中国，CN201410462190.9。

4.   李根喜、赵婧、陈桂芳、刘丽丽、邱焕焕、闫雅琳，检测银离子的生物电化学传感器及其制备方法，2014.8.13，中国，ZL201210075052.6。